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Wade was injured in the first half of Friday’s win over the Orlando Magic. Wade didn’t score a point in 10 minutes before getting hurt.
The Cavaliers said Sunday that imaging tests confirmed an AC joint sprain.
Wade is averaging 6.4 points and 4.1 rebounds in 24.1 minutes per game. He has started nine games as coach J.B. Bickerstaff has been forced to juggle lineups due to injuries.